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Study on increase of nicotinamide mononucleotide yield by site-directed mutagenesis of nicotinamide phosphoribosyltransferase

Nicotinamide phosphoribosyltransferase (NAMPT) was a key rate-limiting enzyme in the biosynthetic pathway of nicotinamide mononucleotide (NMN). In this study, the NAMPT gene derived from Comamonadaceae bacterium was heterologous expressed in Escherichia coli BL21 (DE3). Taking it as the original str...

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Autor principal: DONG Ping, XU Yifan, HOU Ying, LUO Xuegang, ZHANG Lin, QIAO Changsheng
Format: Artigo
Idioma:Inglês
Publicat: Editorial Department of China Brewing 2025-10-01
Col·lecció:Zhongguo niangzao
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Accés en línia:https://manu61.magtech.com.cn/zgnz/fileup/0254-5071/PDF/0254-5071-2025-44-10-36.pdf
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