Proteomic Validation of MEG-01-Derived Extracellular Vesicles as Representative Models for Megakaryocyte- and Platelet-Derived Extracellular Vesicles

Platelets and their extracellular vesicles (EVs) have emerged as promising liquid biopsy biosources for cancer detection and monitoring. The megakaryoblastic MEG-01 cell line offers a controlled system for generating platelet-like particles (PLPs) and EVs through valproic-acid-induced differentiatio...

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Autors principals:	Jose Manuel Sanchez-Manas, Sonia Perales, Gonzalo Martinez-Navajas, Jorge Ceron-Hernandez, Cristina M. Lopez, Angela Peralbo-Molina, Juan R. Delgado, Joaquina Martinez-Galan, Veronica Ramos-Mejia, Eduardo Chicano-Galvez, Maria Hernandez-Valladares, Francisco M. Ortuno, Carolina Torres, Pedro J. Real
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2025-12-01
Col·lecció:	Biomolecules
Matèries:	MEG-01 cell line extracellular vesicles (EVs) platelets proteomics microvesicles (MVs) exosomes (EXOs)
Accés en línia:	https://www.mdpi.com/2218-273X/15/12/1698
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