Exploring redox vulnerabilities in JAK2V617F-positive cellular models
Background: In Philadelphia chromosome-negative myeloproliferative neoplasm (MPN) models, reactive oxygen species (ROS) are elevated and have been implicated in genomic instability, JAK2/STAT signaling amplification, and disease progression. Although the potential effects of ROS on the MPN phenotype...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2021-10-01
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| coleção: | Hematology, Transfusion and Cell Therapy |
| Assuntos: | |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2531137920301255 |
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