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Investigation of Genetic Modifiers of Copper Toxicosis in Labrador Retrievers

Copper toxicosis is a complex genetic disorder in Labrador retrievers characterized by hepatic copper accumulation eventually leading to liver cirrhosis. The variation of hepatic copper levels in Labrador retrievers has been partly explained by mutations in <i>ATP7A</i> c.980C>T and <i>ATP7B</i> c.4...

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Autori principali: Xiaoyan Wu, Elise R. den Boer, Manon Vos-Loohuis, Frank G. van Steenbeek, Glen R. Monroe, Isaäc J. Nijman, Peter. A. J. Leegwater, Hille Fieten
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2020-10-01
Serie:Life
Soggetti:
Wilson disease
Menkes disease
dog
copper
ATP7A
ATP7B
Accesso online:https://www.mdpi.com/2075-1729/10/11/266
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