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Three-Dimensional Model of Sub-Plasmalemmal Ca2+ Microdomains Evoked by the Interplay Between ORAI1 and InsP3 Receptors

Ca2+ signaling plays an essential role in T cell activation, which is a key step to start an adaptive immune response. During the transition from a quiescent to a fully activated state, Ca2+ microdomains characterized by reduced spatial and temporal extents are observed in the junctions between the...

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Bibliografiske detaljer
Principais autores: Diana Gil, Andreas H. Guse, Geneviève Dupont
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-04-01
Serier:Frontiers in Immunology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2021.659790/full
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