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Progress in research on the mechanisms and therapeutic strategies of SLC7A11 regulation in glioma

Abstract This review summarizes the critical role of SLC7A11 in the pathogenesis of glioma and its potential as a therapeutic target. By mediating cystine uptake and glutamate release, SLC7A11 promotes glutathione (GSH) synthesis, protecting glioma cells from oxidative stress-induced damage and main...

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Principais autores: Qianfeng Wei, Bangfa Xiong, Guangming Yang, Jiahui Wang, Erqing Chai
Formato: Artigo
Idioma:Inglês
Publicado: Springer 2025-12-01
Series:Discover Oncology
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Acceso en liña:https://doi.org/10.1007/s12672-025-04154-y
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