Set of 15 SNP-SNP Markers for Detection of Unbalanced Degraded DNA Mixtures and Noninvasive Prenatal Paternity Testing

Unbalanced and degraded mixtures (UDM) are very common in forensic DNA analysis. For example, DNA signals from criminal suspects are masked by a large amount of DNA from victims, or cell-free fetal DNA (cffDNA) in maternal plasma is masked by a high background of maternal DNA. Currently, detecting m...

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Autori principali:	Ranran Zhang, Yu Tan, Li Wang, Hui Jian, Jing Zhu, Yuanyuan Xiao, Mengyu Tan, Jiaming Xue, Fan Yang, Weibo Liang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2022-02-01
Serie:	Frontiers in Genetics
Soggetti:	SNP-SNP microhaplotype amplification-refractory mutation system PCR SNaPshot unbalanced and degraded mixture cell-free fetal DNA noninvasive prenatal paternity testing
Accesso online:	https://www.frontiersin.org/articles/10.3389/fgene.2021.800598/full
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