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Quantitative profiling brain proteomes revealed mitochondrial dysfunction in Alzheimer’s disease

Abstract Mitochondrial dysfunction is a key feature in both aging and neurodegenerative diseases including Alzheimer’s disease (AD), but the molecular signature that distinguishes pathological changes in the AD from healthy aging in the brain mitochondria remain poorly understood. In order to unveil...

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Autors principals: Sunil S Adav, Jung Eun Park, Siu Kwan Sze
Format: Artigo
Idioma:Inglês
Publicat: BMC 2019-01-01
Col·lecció:Molecular Brain
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Accés en línia:http://link.springer.com/article/10.1186/s13041-019-0430-y
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