Aggresome formation promotes ASK1/JNK signaling activation and stemness maintenance in ovarian cancer

Abstract Aggresomes are the product of misfolded protein aggregation, and the presence of aggresomes has been correlated with poor prognosis in cancer patients. However, the exact role of aggresomes in tumorigenesis and cancer progression remains largely unknown. Herein, the multiomics screening rev...

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Detalhes bibliográficos

Principais autores:	Yurou Chen, Yulong Qiang, Jiachen Fan, Qian Zheng, Leilei Yan, Guanlan Fan, Xiaofei Song, Nan Zhang, Qiongying Lv, Jiaqiang Xiong, Jingtao Wang, Jing Cao, Yanyan Liu, Jie Xiong, Wei Zhang, Feng Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2024-02-01
coleção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-024-45698-x
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