A novel small molecule inhibitor of MDM2-p53 (APG-115) enhances radiosensitivity of gastric adenocarcinoma
Abstract Background Gastric cancer is the leading cause of cancer related death worldwide. Radiation alone or combined with chemotherapy plays important role in locally advanced and metastatic gastric adenocarcinoma. MDM2–p53 interaction and downstream signaling affect cellular response to DNA damag...
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| Principais autores: | , , , , , , , , , , , , |
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| 格式: | Artigo |
| 语言: | Inglês |
| 出版: |
BMC
2018-05-01
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| 丛编: | Journal of Experimental & Clinical Cancer Research |
| 主题: | |
| 在线阅读: | http://link.springer.com/article/10.1186/s13046-018-0765-8 |
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