Improved Inhibitors Targeting the Thymidylate Kinase of Multidrug-Resistant <i>Mycobacterium tuberculosis</i> with Favorable Pharmacokinetics

This study aims to design improved inhibitors targeting the thymidylate kinase (TMK) of <i>Mycobacterium tuberculosis</i> (<i>Mtb</i>), the causative agent of infectious disease tuberculosis that is associated with high morbidity and mortality in developing countries. TMK is an essential enzyme for...

Olles dieđut

Bibliográfalaš dieđut

Váldodahkkit:	Souleymane Konate, Koffi N’Guessan Placide Gabin Allangba, Issouf Fofana, Raymond Kre N’Guessan, Eugene Megnassan, Stanislav Miertus, Vladimir Frecer
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	MDPI AG 2025-01-01
Ráidu:	Life
Fáttát:	tuberculosis <i>Mycobacterium tuberculosis</i> thymidylate kinase molecular modelling MM-PBSA QSAR model of inhibition in vitro
Liŋkkat:	https://www.mdpi.com/2075-1729/15/2/173
Fáddágilkorat:	Lasit fáddágilkoriid Eai fáddágilkorat, Lasit vuosttaš fáddágilkora!