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Increased Nucleosomes and Neutrophil Activation Link to Disease Progression in Patients with Scrub Typhus but Not Murine Typhus in Laos.

Cell-mediated immunity is essential in protection against rickettsial illnesses, but the role of neutrophils in these intracellular vasculotropic infections remains unclear. This study analyzed the plasma levels of nucleosomes, FSAP-activation (nucleosome-releasing factor), and neutrophil activation...

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Detalhes bibliográficos
Principais autores: Daniel H Paris, Femke Stephan, Ingrid Bulder, Diana Wouters, Tom van der Poll, Paul N Newton, Nicholas P J Day, Sacha Zeerleder
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2015-01-01
coleção:PLoS Neglected Tropical Diseases
Acesso em linha:http://europepmc.org/articles/PMC4552835?pdf=render
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