Gene-centered identification of cis-regulatory islands highlights regulatory landscapes complementary to motif-centric approaches
Abstract Background Cis-regulatory elements constitute a fundamental layer of gene regulation, yet their computational identification has largely relied on transcription factor (TF)-centric frameworks that assume genome-wide background normalization and explicit TF binding models. While effective at...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2026-04-01
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| Colecção: | BMC Genomics |
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| Acesso em linha: | https://doi.org/10.1186/s12864-026-12846-0 |
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