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The unilateral involution in the thymus of a 96-year-old male leads to the preservation of structural integrity in one thymic lobe, as assessed by the expression of medullar and cortical antigens and the presence of CD3+ cells

The process of thymic involution begins soon after birth and continues through adult life. Although evolutionary conserved in all vertebrates, the thymic involution has no defined kinetics. Little is known about the pace of its regression in humans, except that there is a marked increase of thymic i...

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Autori principali: Pranuthi Kanneganti, Joseph Lyle, Julia H. Smith, Heather McGuire, Richaela Denlinger, Malgorzata Simm
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2022-11-01
Serie:Heliyon
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Accesso online:http://www.sciencedirect.com/science/article/pii/S2405844022030225
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