Characterization of mitochondrial DNA heteroplasmy using a parallel sequencing system
Characterization of human mitochondrial genome sequences is important for the molecular diagnosis of mitochondrial diseases, especially in samples with a low level of mitochondrial DNA (mtDNA) heteroplasmy (≥5%). Currently, no single methodology can simultaneously determine complete mtDNA sequences,...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis Group
2010-04-01
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| Serie: | BioTechniques |
| Soggetti: | |
| Accesso online: | https://www.future-science.com/doi/10.2144/000113389 |
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