Establishment of functional epithelial organoids from human lacrimal glands

Abstract Background Tear deficiency due to lacrimal gland (LG) dysfunction is one of the major causes of dry eye disease (DED). Therefore, LG stem cell-based therapies have been extensively reported to regenerate injured lacrimal tissue; however, the number of stem cells in the LG tissue is low, and...

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Principais autores:	Sang Yun Jeong, Woo Hee Choi, Seong Gyeong Jeon, Sookon Lee, Jong-Moon Park, Mira Park, Hookeun Lee, Helen Lew, Jongman Yoo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2021-04-01
coleção:	Stem Cell Research & Therapy
Assuntos:	Organoid Lacrimal gland Dry eye disease Sjogren syndrome
Acesso em linha:	https://doi.org/10.1186/s13287-021-02133-y
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