Contribution of Common Genetic Variants to Familial Aggregation of Disease and Implications for Sequencing Studies.
Despite genetics being accepted as the primary cause of familial aggregation for most diseases, it is still unclear whether afflicted families are likely to share a single highly penetrant rare variant, many minimally penetrant common variants, or a combination of the two types of variants. We there...
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| Principais autores: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2019-11-01
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| coleção: | PLoS Genetics |
| Acesso em linha: | https://doi.org/10.1371/journal.pgen.1008490 |
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