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Single-Cell RNA-seq Reveals Angiotensin-Converting Enzyme 2 and Transmembrane Serine Protease 2 Expression in TROP2+ Liver Progenitor Cells: Implications in Coronavirus Disease 2019-Associated Liver Dysfunction

The recent coronavirus disease 2019 (COVID-19) pandemic is caused by severe acute respiratory syndrome coronavirus 2. COVID-19 was first reported in China (December 2019) and is now prevalent across the globe. Entry of severe acute respiratory syndrome coronavirus 2 into mammalian cells requires the...

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Principais autores: Justine Jia Wen Seow, Rhea Pai, Archita Mishra, Edwin Shepherdson, Tony Kiat Hon Lim, Brian K. P. Goh, Jerry K. Y. Chan, Pierce K. H. Chow, Florent Ginhoux, Ramanuj DasGupta, Ankur Sharma
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-04-01
coleção:Frontiers in Medicine
Assuntos:
SARS-CoV-2
COVID-19
ACE2
tmprss2
Trop2
liver
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmed.2021.603374/full
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