Collider bias correction for multiple covariates in GWAS using robust multivariable Mendelian randomization.
Genome-wide association studies (GWAS) have identified many genetic loci associated with complex traits and diseases in the past 20 years. Multiple heritable covariates may be added into GWAS regression models to estimate direct effects of genetic variants on a focal trait, or to improve the power b...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
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Public Library of Science (PLoS)
2024-04-01
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| Edice: | PLoS Genetics |
| On-line přístup: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1011246&type=printable |
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