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Humoral Alloimmunity in Transplantation: Relevance of HLA Epitope Antigenicity and Immunogenicity

HLA mismatching is an important risk factor for antibody-mediated rejection and transplant failure. With the realization HLA antibodies recognize epitopes rather than antigens, it has become apparent that donor-recipient compatibility should be assessed at the epitope level. Recent developments have...

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Bibliografiske detaljer
Hovedforfatter: Rene J Duquesnoy
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2011-11-01
Serier:Frontiers in Immunology
Fag:
Online adgang:http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00059/full
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