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New-generation advanced PROTACs as potential therapeutic agents in cancer therapy

Abstract Proteolysis-targeting chimeras (PROTACs) technology has garnered significant attention over the last 10 years, representing a burgeoning therapeutic approach with the potential to address pathogenic proteins that have historically posed challenges for traditional small-molecule inhibitors....

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Auteurs principaux: Chao Wang, Yujing Zhang, Wujun Chen, Yudong Wu, Dongming Xing
Format: Artigo
Langue:Inglês
Publié: BMC 2024-05-01
Collection:Molecular Cancer
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Accès en ligne:https://doi.org/10.1186/s12943-024-02024-9
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