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Comparison of 18F-T807 and 18F-THK5117 PET in a Mouse Model of Tau Pathology

Positron-emission-tomography (PET) imaging of tau pathology has facilitated development of anti-tau therapies. While members of the arylquinoline and pyridoindole families have been the most frequently used tau radioligands so far, analyses of their comparative performance in vivo are scantly docume...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Matthias Brendel, Behrooz H. Yousefi, Tanja Blume, Michael Herz, Carola Focke, Maximilian Deussing, Finn Peters, Simon Lindner, Barbara von Ungern-Sternberg, Alexander Drzezga, Peter Bartenstein, Christian Haass, Nobuyuki Okamura, Jochen Herms, Igor Yakushev, Axel Rominger
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018-06-01
Schriftenreihe:Frontiers in Aging Neuroscience
Schlagworte:
tau
small animal PET
transgenic mice
18F-T807
18F-THK5117
Online-Zugang:https://www.frontiersin.org/article/10.3389/fnagi.2018.00174/full
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