Persistent immune dysfunction during suppressive antiretroviral therapy: implications for analytical treatment interruption trials for chronic HIV infections in sub-Saharan Africa

BackgroundDespite the success of long-term antiretroviral therapy (ART), immune dysfunction—including incomplete T helper cell recovery, immune activation, and inflammation—persists and may affect the benefits of analytical ART treatment interruption (ATI) trials among people living with human immun...

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Detalhes bibliográficos

Principais autores:	Patricia Kankundiye, Praiscillia Kia, Edward Kankaka, Rose Nabatanzi, Tokameh Mahmoudi, Damalie Nakanjako
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-03-01
coleção:	Frontiers in Immunology
Assuntos:	broadly neutralizing antibodies (bnAbs) chronic HIV infections HIV cure HIV immunotherapy HIV treatment interruption persistent HIV-associated immune dysfunction
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1754996/full
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