Scopoletin and umbelliferone from Cortex Mori as protective agents in high glucose-induced mesangial cell as in vitro model of diabetic glomerulosclerosis

Two known coumarins, scopoletin (SP) and umbelliferone (UB), were isolated from Cortex Mori (CM). Their structures were elucidated by various spectroscopic analyses. Then, their effects on rat glomerular mesangial cells (RGMCs, HBZY-1) proliferation, hypertrophy, extracellular matrix (ECM) prolifera...

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Detalhes bibliográficos

Principais autores:	Yijun Liang, Xuxin Zeng, Jialiang Guo, Hui Liu, Bao He, Renyu Lai, Quan Zhu, Zhaoguang Zheng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wolters Kluwer Medknow Publications 2021-01-01
coleção:	Chinese Journal of Physiology
Assuntos:	cortex mori diabetic kidney disease glomerulosclerosis proliferation rat glomerular mesangial cells scopoletin umbelliferone
Acesso em linha:	http://www.cjphysiology.org/article.asp?issn=0304-4920;year=2021;volume=64;issue=3;spage=150;epage=158;aulast=Liang
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