The cGAS Paradox: Contrasting Roles for cGAS-STING Pathway in Chromosomal Instability

Chromosomal instability (CIN) is an intricate phenomenon that is often found in human cancer, characterized by persisting errors in chromosome segregation. This ongoing chromosome mis-segregation results in structural and numerical chromosomal abnormalities that have been widely described to promote...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Christy Hong, Andrea E. Tijhuis, Floris Foijer
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2019-10-01
Schriftenreihe:	Cells
Schlagworte:	mitosis cgas sting chromosomal instability aneuploidy
Online-Zugang:	https://www.mdpi.com/2073-4409/8/10/1228
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