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Comparative Assessment of Protein Kinase Inhibitors in Public Databases and in PKIDB

Since the first approval of a protein kinase inhibitor (PKI) by the Food and Drug Administration (FDA) in 2001, 55 new PKIs have reached the market, and many inhibitors are currently being evaluated in clinical trials. This is a clear indication that protein kinases still represent major drug target...

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Autori principali: Colin Bournez, Fabrice Carles, Gautier Peyrat, Samia Aci-Sèche, Stéphane Bourg, Christophe Meyer, Pascal Bonnet
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2020-07-01
Serie:Molecules
Soggetti:
protein kinase inhibitors
clinical trials
approved drugs
database
chemometrics analysis
kinome
Accesso online:https://www.mdpi.com/1420-3049/25/14/3226
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