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Nuclear PTEN Regulates Thymidylate Biosynthesis in Human Prostate Cancer Cell Lines

The phosphatase and tensin homologue deleted on chromosome 10 (PTEN) tumor suppressor governs a variety of biological processes, including metabolism, by acting on distinct molecular targets in different subcellular compartments. In the cytosol, inactive PTEN can be recruited to the plasma membrane...

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Principais autores: Zoe N. Loh, Mu-En Wang, Changxin Wan, John M. Asara, Zhicheng Ji, Ming Chen
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-08-01
Serier:Metabolites
Fag:
nuclear PTEN
metabolic compartmentalization
thymidylate biosynthesis
cancer
Online adgang:https://www.mdpi.com/2218-1989/13/8/939
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