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Goatpox virus Hrf-063 interacts with host eIF4A1 and is associated with altered expression of antiviral signaling-related factors

Goatpox virus (GTPV) is an important capripoxvirus that causes severe disease in goats, yet the functions of many GTPV-encoded proteins remain unclear. In this study, eukaryotic translation initiation factor 4A1 (eIF4A1) was identified as a host protein interacting with GTPV Hrf-063 by GST pull-down...

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Main Authors: Baoqin Long, Huixiang Wang, Linjin Yu, Bo Liu, Mengjiao Xu, Haerleha Amantai, Weiqian Tian, Haoran Chen, Haolai Qin, Yahui Han, Longxing Shi, Jingxin Gu, Mingxuan Tang, Zhiyi Ge, Jia Chen, Youwen Li
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2026-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
antiviral signaling
Capripoxvirus
eIF4A1
goatpox virus
host-virus interaction
Hrf-063
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2026.1840976/full
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