Insights into Hunter syndrome from the structure of iduronate-2-sulfatase
Hunter syndrome is a lysosomal storage disease caused by mutations in the enzyme iduronate-2-sulfatase (IDS). Here, the authors present the IDS crystal structure and give mechanistic insights into mutations that cause Hunter syndrome.
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Portfolio
2017-06-01
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| Col·lecció: | Nature Communications |
| Accés en línia: | https://doi.org/10.1038/ncomms15786 |
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