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The Structures and Binding Modes of Small-Molecule Inhibitors of <i>Pseudomonas aeruginosa</i> Elastase LasB

Elastase B (LasB) is a zinc metalloprotease and a crucial virulence factor of <i>Pseudomonas aeruginosa</i>. As the need for new strategies to fight antimicrobial resistance (AMR) constantly rises, this protein has become a key target in the development of novel antivirulence agents. The extensive k...

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Bibliografische Detailangaben
Hauptverfasser: Virgyl Camberlein, Gwenaëlle Jézéquel, Jörg Haupenthal, Anna K. H. Hirsch
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2022-08-01
Schriftenreihe:Antibiotics
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Online-Zugang:https://www.mdpi.com/2079-6382/11/8/1060
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