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Alzheimer's Disease: The Role of Microglia in Brain Homeostasis and Proteopathy

Brain aging is central to late-onset Alzheimer's disease (LOAD), although the mechanisms by which it occurs at protein or cellular levels are not fully understood. Alzheimer's disease is the most common proteopathy and is characterized by two unique pathologies: senile plaques and neurofibrillary ta...

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Autori principali: Kevin A. Clayton, Alicia A. Van Enoo, Tsuneya Ikezu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017-12-01
Serie:Frontiers in Neuroscience
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Accesso online:http://journal.frontiersin.org/article/10.3389/fnins.2017.00680/full
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