Proctocolectomy with permanent ileostomy is associated with improved transplant-free survival in patients with PSC

Background & Aims: The gut–liver axis is believed to be crucial in the pathogenesis of primary sclerosing cholangitis (PSC). However, the impact of colectomy on liver disease progression is unclear. Our study estimated the effect of colectomy on PSC progression with correction for time dependenc...

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Principais autores:	Bregje Mol, Moyrha van Nieuwamerongen, Kim N. van Munster, Martti Färkkilä, Trine Folseraas, Sara K.V. Tjønnfjord, Johannes R. Hov, Kirsten Boberg, Mette Vesterhus, Kristin K. Jørgensen, Annika Bergquist, Jorn C. Goet, Annemarie C. de Vries, Adriaan J.P. van der Meer, Rinse K. Weersma, Akin Inderson, Johannes A. Bogaards, Cyriel Y. Ponsioen
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Elsevier 2026-03-01
סדרה:	JHEP Reports
נושאים:	Primary sclerosing cholangitis Inflammatory bowel disease Colectomy
גישה מקוונת:	http://www.sciencedirect.com/science/article/pii/S2589555925003830
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