The CD38+HLA-DR+ T cells with activation and exhaustion characteristics as predictors of severity and mortality in COVID-19 patients

BackgroundThe COVID-19 pandemic remains a global health challenge. Severe cases often respond poorly to standard treatments, highlighting the necessity for novel therapeutic targets and early predictive biomarkers.MethodsWe utilized flow cytometry to analyze peripheral immune cells from healthy, bac...

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Detalhes bibliográficos

Principais autores:	Qiuyue Long, Shixu Song, Jianbo Xue, Wenyi Yu, Yaolin Zheng, Jiwei Li, Jing Wu, Xiaoyi Hu, Mingzheng Jiang, Hongli Ye, Binghan Zheng, Minghui Wang, Fangfang Wu, Ke Li, Zhancheng Gao, Yali Zheng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-04-01
Colecção:	Frontiers in Immunology
Assuntos:	COVID-19 CD38+HLA-DR+ T cells T cells single-cell transcriptomics mortality risk factor
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1577803/full
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