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Serum Sphingolipid Variations Associate with Hepatic Decompensation and Survival in Patients with Cirrhosis.

Sphingolipids constitute bioactive molecules with functional implications in liver homeostasis. Particularly, ablation of very long chain ceramides in a knockout mouse model has been shown to cause a severe hepatopathy.We aimed to evaluate the serum sphingolipid profile of 244 patients with cirrhosi...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Georgios Grammatikos, Nerea Ferreiròs, Oliver Waidmann, Dimitra Bon, Sirkka Schroeter, Alexander Koch, Eva Herrmann, Stefan Zeuzem, Bernd Kronenberger, Josef Pfeilschifter
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science (PLoS) 2015-01-01
Sarja:PLoS ONE
Linkit:http://europepmc.org/articles/PMC4575185?pdf=render
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