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Toll-Like Receptor 4 Activation Prevents Rat Cardiac Fibroblast Death Induced by Simulated Ischemia/Reperfusion

Death of cardiac fibroblasts (CFs) by ischemia/reperfusion (I/R) has major implications for cardiac wound healing. In in vivo models of myocardial infarction, toll-like receptor 4 (TLR4) activation has been reported as a cardioprotector; however, it remains unknown whether TLR4 activation can preven...

Celý popis

Uloženo v:
Hlavní autoři: Pablo Parra-Flores, Jenaro Espitia-Corredor, Claudio Espinoza-Pérez, Cristian Queirolo, Pedro Ayala, Francisca Brüggendieck, Aimee Salas-Hernández, Viviana Pardo-Jiménez, Guillermo Díaz-Araya
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021-06-01
Edice:Frontiers in Cardiovascular Medicine
Témata:
cardiac fibroblasts
ischemia/reperfusion
TLR4
LPS
apoptosis
On-line přístup:https://www.frontiersin.org/articles/10.3389/fcvm.2021.660197/full
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