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Gadolinium(III)-DOTA Complex Functionalized with BODIPY as a Potential Bimodal Contrast Agent for MRI and Optical Imaging

The synthesis and characterization of a novel gadolinium(III) DOTA complex functionalized with a boron-dipyrromethene derivative (BODIPY) is described. The assembly of the complex relies on azide diazotransfer chemistry in a copper tube flow reactor. The azide thus formed is coupled directly with an...

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Principais autores: Matthias Ceulemans, Koen Nuyts, Wim M. De Borggraeve, Tatjana N. Parac-Vogt
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2015-11-01
Serier:Inorganics
Fag:
Gadolinium(III)
BODIPY
click chemistry
MRI
contrast agent
Online adgang:http://www.mdpi.com/2304-6740/3/4/516
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