The mrp-3 gene is involved in haem efflux and detoxification in a blood-feeding nematode

Abstract Background Haem is essential but toxic for metazoan organisms. Auxotrophic nematodes can acquire sufficient haem from the environment or their hosts in the meanwhile eliminate or detoxify excessive haem through tightly controlled machinery. In previous work, we reported a role of the unique...

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Detalhes bibliográficos

Principais autores:	Danni Tong, Fei Wu, Xueqiu Chen, Zhendong Du, Jingru Zhou, Jingju Zhang, Yi Yang, Aifang Du, Guangxu Ma
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2024-09-01
coleção:	BMC Biology
Assuntos:	Haematophagous nematodes Mrp Haem efflux Haem detoxification Target candidate
Acesso em linha:	https://doi.org/10.1186/s12915-024-02001-0
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