Targeting Cytotoxin-Associated Antigen A, a Virulent Factor of <i>Helicobacter pylori</i>-Associated Gastric Cancer: Structure-Based In Silico Screening of Natural Compounds

Gastric cancer is the fifth most frequent cancer and the third major cause of mortality worldwide. <i>Helicobacter pylori</i>, a bacterial infection linked with GC, injects the cytotoxin-associated antigen A (CagA; an oncoprotein) into host cells. When the phosphorylated CagA protein enters the cell...

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Autors principals:	Shan He, Abdulraheem Ali Almalki, Misbahuddin M. Rafeeq, Ziaullah M. Sain, Amany I. Alqosaibi, Mashael M. Alnamshan, Ibtesam S. Al-Dhuayan, Abdul Rahaman, Yang Zhang, Hamsa Jameel Banjer, Farah Anjum, Haitham Ali M. Alzghaibi, Ali H. Alharbi, Qazi Mohammad Sajid Jamal
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2022-01-01
Col·lecció:	Molecules
Matèries:	gastric cancer CagA natural compounds virtual screening
Accés en línia:	https://www.mdpi.com/1420-3049/27/3/732
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