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The synergistic effect of imipenem combined with ceftazidime-avibactam against Klebsiella pneumoniae with alternating resistance to CZA and carbapenem

Purposes: The purpose of this study was to explore the mechanisms of resistance of clinically isolated K. pneumoniae, which is alternately resistant to carbapenems and ceftazidime/avibactam (CZA), and therapeutic strategies. Methods: Whole-genome sequencing was used to determine the resistance mecha...

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Auteurs principaux: Yun-Ying Wang, Min Jiang, Shuang-Juan Liu, Wei Wei, Xiao-Hui Zhan, Di Mu
Format: Artigo
Langue:Inglês
Publié: Elsevier 2025-12-01
Collection:Journal of Microbiology, Immunology and Infection
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Accès en ligne:http://www.sciencedirect.com/science/article/pii/S1684118225000854
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