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Glycogen synthase kinase 3 inhibition controls Mycobacterium tuberculosis infection

Summary: Compounds targeting host control of infectious diseases provide an attractive alternative to antimicrobials. A phenotypic screen of a kinase library identified compounds targeting glycogen synthase kinase 3 as potent inhibitors of Mycobacterium tuberculosis (Mtb) intracellular growth in the...

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Autors principals: Sandra Peña-Díaz, Joseph D. Chao, Celine Rens, Hasti Haghdadi, Xingji Zheng, Keegan Flanagan, Mary Ko, Tirosh Shapira, Adrian Richter, Danay Maestre-Batlle, Julio Ortiz Canseco, Maximiliano Gabriel Gutierrez, Khanh Dao Duc, Steven Pelech, Yossef Av-Gay
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2024-08-01
Col·lecció:iScience
Matèries:
Molecular biology
Microbiology
Medical Microbiology
Accés en línia:http://www.sciencedirect.com/science/article/pii/S2589004224017802
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