Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S

Endoglycosidase S only recognizes one particular type of glycan within IgG antibodies but the molecular basis for this high specificity is not fully understood. Here, the authors present the crystal structure of product-bound Endoglycosidase S, revealing the determinants for its glycan specificity.

Dades bibliogràfiques

Autors principals:	Beatriz Trastoy, Erik Klontz, Jared Orwenyo, Alberto Marina, Lai-Xi Wang, Eric J. Sundberg, Marcelo E. Guerin
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2018-05-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-018-04300-x
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