Evaluating the accuracy of amplicon-based microbiome computational pipelines on simulated human gut microbial communities

Abstract Background Microbiome studies commonly use 16S rRNA gene amplicon sequencing to characterize microbial communities. Errors introduced at multiple steps in this process can affect the interpretation of the data. Here we evaluate the accuracy of operational taxonomic unit (OTU) generation, ta...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Jonathan L. Golob, Elisa Margolis, Noah G. Hoffman, David N. Fredricks
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2017-05-01
Цуврал:	BMC Bioinformatics
Нөхцлүүд:	Microbiome Classification Operational taxonomic unit Optimization UniFrac QIIME
Онлайн хандалт:	http://link.springer.com/article/10.1186/s12859-017-1690-0
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!