Syngap1 regulates the synaptic drive and membrane excitability of Parvalbumin-positive interneurons in mouse auditory cortex

SYNGAP1 haploinsufficiency-related intellectual disability (SYNGAP1-ID) is characterized by moderate to severe ID, generalized epilepsy, autism spectrum disorder, sensory processing dysfunction, and other behavioral abnormalities. While numerous studies have highlighted a role of Syngap1 in cortical...

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Detalles Bibliográficos

Principais autores:	Ruggiero Francavilla, Bidisha Chattopadhyaya, Jorelle Linda Damo Kamda, Vidya Jadhav, Said Kourrich, Jacques L Michaud, Graziella Di Cristo
Formato:	Artigo
Idioma:	Inglês
Publicado:	eLife Sciences Publications Ltd 2025-08-01
Series:	eLife
Assuntos:	intrinsic properties cortical GABAergic interneurons glutamatergic synapses auditory cortex Syngap1
Acceso en liña:	https://elifesciences.org/articles/97100
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