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The role of RICTOR downstream of receptor tyrosine kinase in cancers

Abstract The importance of the network defined by phosphatidylinositol-3-kinase (PI3K), AKT and mammalian target of rapamycin (mTOR) downstream of Receptor Tyrosine Kinase (RTK) has been known for many years but the central role of RICTOR (rapamycin-insensitive companion of mTOR) in this pathway is...

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Bibliografiske detaljer
Principais autores: Ahlem Jebali, Nicolas Dumaz
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2018-02-01
Serier:Molecular Cancer
Fag:
Online adgang:http://link.springer.com/article/10.1186/s12943-018-0794-0
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