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The cytoplasmic-nuclear transport of DDX3X promotes immune-mediated liver injury in mice regulated by endoplasmic reticulum stress

Abstract Immune-mediated liver injury is a common characteristic of various liver diseases, including autoimmune and viral hepatitis. Here, we investigated the role of DEAD-box helicase 3, X-linked (DDX3X) in immune-mediated liver injury. Liver injury was induced in C57BL/6J mice via concanavalin A...

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Bibliografische gegevens
Hoofdauteurs: Zihao Fan, Ling Xu, Yao Gao, Yaling Cao, Yuan Tian, Zhenzhen Pan, Linlin Wei, Sisi Chen, Xiangying Zhang, Mei Liu, Feng Ren
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2024-09-01
Reeks:Cell Death and Disease
Online toegang:https://doi.org/10.1038/s41419-024-07076-9
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