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Increased oxidative metabolism and neurotransmitter cycling in the brain of mice lacking the thyroid hormone transporter SLC16A2 (MCT8).

Mutations of the monocarboxylate transporter 8 (MCT8) cause a severe X-linked intellectual deficit and neurological impairment. MCT8 is a specific thyroid hormone (T4 and T3) transporter and the patients also present unusual abnormalities in the serum profile of thyroid hormone concentrations due to...

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Príomhchruthaitheoirí: Tiago B Rodrigues, Ainhoa Ceballos, Carmen Grijota-Martínez, Barbara Nuñez, Samuel Refetoff, Sebastian Cerdán, Beatriz Morte, Juan Bernal
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Public Library of Science (PLoS) 2013-01-01
Sraith:PLoS ONE
Rochtain ar líne:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0074621&type=printable
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