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The first-line antihypertensive nitrendipine potentiated the therapeutic effect of oxaliplatin by downregulating CACNA1D in colorectal cancer

Oxaliplatin (OXA) is among the most common chemotherapy drugs and is the base component of the FOLFOX regimen (OXA + leucovorin + 5-fluorouracil) and CapeOX regimen (OXA + capecitabine). Resistance to and failure of these two OXA-based regimens often results in poor outcomes in patients with colorec...

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Bibliografische gegevens
Hoofdauteurs: Lai Chengzhe, Liu Jinghu, Zhou Jingna, Zhou Haokun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: De Gruyter 2025-02-01
Reeks:Open Medicine
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Online toegang:https://doi.org/10.1515/med-2024-1138
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