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CRISPR Screen Reveals PACT as a Pro-Viral Factor for Dengue Viral Replication

The dengue virus is a single-stranded, positive-sense RNA virus that infects ~400 million people worldwide. Currently, there are no approved antivirals available. CRISPR-based screening methods have greatly accelerated the discovery of host factors that are essential for DENV infection and that can...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Shwetha Shivaprasad, Wenjie Qiao, Kuo-Feng Weng, Pavithra Umashankar, Jan E. Carette, Peter Sarnow
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2024-05-01
Schriftenreihe:Viruses
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Online-Zugang:https://www.mdpi.com/1999-4915/16/5/725
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