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Therapeutic Effects of WT1 Silencing via Respiratory Administration of Neutral DOPC Liposomal-siRNA in a Lung Metastasis Melanoma Murine Model

The lungs represent a frequent target for metastatic melanoma as they offer a high-oxygen environment for tumor development. The overexpression of the WT1 protein has been associated with the occurrence of melanoma. In this study, we evaluated the effects of silencing the WT1 protein by siRNA in bot...

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Bibliographic Details
Main Authors: Martin R. Ramos-Gonzalez, Eduardo Vazquez-Garza, Gerardo Garcia-Rivas, Cristian Rodriguez-Aguayo, Arturo Chavez-Reyes
Format: Artigo
Language:Inglês
Published: MDPI AG 2023-03-01
Series:Non-Coding RNA
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Online Access:https://www.mdpi.com/2311-553X/9/2/21
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