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Discovery and Characterization of Phage Display-Derived Human Monoclonal Antibodies against RSV F Glycoprotein.

Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infection in infants, the elderly and in immunosuppressed populations. The vast majority of neutralizing antibodies isolated from human subjects target the RSV fusion (F) glycoprotein, making it an attractive target for...

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Autori principali: Zhifeng Chen, Lan Zhang, Aimin Tang, Cheryl Callahan, Pavlo Pristatsky, Ryan Swoyer, Pedro Cejas, Debbie Nahas, Jennifer Galli, Scott Cosmi, Daniel DiStefano, Van M Hoang, Andrew Bett, Danilo Casimiro, Kalpit A Vora
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2016-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC4892554?pdf=render
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